2025

• Spatial and morphological distribution of brain metastases by anatomical, functional and vascular atlases to guide detection, segmentation and therapy, Jorge Barrios; Evan Porter; Dante Capaldi; Taman Upadhaya; William C. Chen; Julian R. Perks; Aditya Apte; Michalis Aristophanous; Eve LoCastro; Dylan Hsu; Payton H. Stone; Javier E. Villanueva-Meyer; Gilmer Valdes; Fei Jiang; Michael Maddalena; Hui Lin; Oi Wai Chau; Benjamin Ziemer; Maasa Seaberg; Penny Sneed; Jean Nakamura; Lauren Boreta; Shannon Fogh; David Raleigh; Jessica Chew; Harish Vasudevan; Soonmee Cha; Christopher Hess; ; Ruben Fragoso; David B Shultz; Luke Pike; Shawn Hervey-Jumper; Derek S Tsang, MD; Philip Theodosopoulos; Jinger Y. Sun; Muhtada A. K. Aldin; Daniel Cooke, MD; Stanley H. Benedict; Ke Sheng; Jan Seuntjens; Catherine Coolens; Joe Deasy; Steve Braunstein; and Olivier Morin, Nature Communciations 2025 Accepted
• Multi-contrast 4DMR via MR Multitasking: Early Clinical Experience and Implication for Liver Stereotactic Body Radiation Therapy, Oi Wai April Chau, Theodore Geoghegan, Joshua Everts, Junzhou Chen, Mary Feng, William C Chen, Jessica E. Scholey, Yang Yang, Michael Ohliger, Ke Sheng, Xin Miao, Zhaoyang Fan, Wensha Yang, Radiotherapy and Oncology, 2025 https://doi.org/10.1016/j.radonc.2025.110839
• Real-time Lung Extraction from Synthesized X-rays Improves Pulmonary Image-guided Radiotherapy, Xinyi Fu, Katelyn Hasse, Di Xu, Qifan Xu, Martina Descovich, Dan Ruan and Ke Sheng, Physics in Medicine and Biology, DOI 10.1088/1361-6560/ada719

2024

• D. Xu, Q. Lyu, D. Ruan and K. Sheng, "A Two-Step Framework for Multi-Material Decomposition of Dual Energy Computed Tomography from Projection Domain," 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Orlando, FL, USA, 2024, pp. 1-7, doi: 10.1109/EMBC53108.2024.10782757.
• Robust Automated Mouse Micro-CT Segmentation Using Swin UNEt TRansformers L Jiang, D Xu, Q Xu, A Chatziioannou, KS Iwamoto, S Hui, K Sheng Bioengineering 11 (12), 1255
• Deep learning for MRI-based radiation therapy of prostate cancer: current status, Jess Scholey, Abhejit Rajagopal, Julian Hong, Peder Larson, Ke Sheng, Reviews in Urology, 2024
• MUsculo-Skeleton-Aware (MUSA) Deep Learning for Anatomically Guided Head-and-Neck CT Deformable Registration, Hengjie Liu, Elizabeth McKenzie, Robert K. Chin, Di Xu, Qifan Xu, Dan Ruan, Ke Sheng, Medical Image Analysis, 2024, https://doi.org/10.1016/j.media.2024.103351
• Robust Localization of Poorly Visible Tumor in Fiducial Free Stereotactic Body Radiation Therapy, Di Xu, Martina Descovich, Hengjie Liu and Ke Sheng, Radiotherapy and Oncology 2024
• Anatomy-Constrained Synthesis for Spleen Segmentation Improvement in Unpaired Mouse Micro-CT Scans with 3D CycleGAN, Lu Jiang, Di Xu, and Ke Sheng, Biomed. Phys. Eng. Express 10 055019, https://doi.org/10.1088/2057-1976/ad6a63
• Multi-modal fusion and feature enhancement U-Net coupling with stem cell niches proximity estimation for voxel-wise GBM recurrence prediction, Changzhe Jiao, Yi Lao, Wenwen Zhang, Steve Braunstein, Mia Salans, Javier Villanueva-Meyer, Shawn L Hervey-Jumper, Bo Yang, Olivier Morin, Gilmer Valdes, Zhaoyang Fan, Mark Shiroishi, Gabriel Zada, Ke Sheng and Wensha Yang, 2024 Phys. Med. Biol. 69 155021, DOI 10.1088/1361-6560/ad64b8
• Quantification of dosimetry improvement with or without patient surface guidance, Ke Sheng, Minsong Cao, Andrew Godley, Mu-Han Lin, Lukas Henze, Laura Hammond, Laurence Delombaerde, Kirsten Hierholz, Jana Kouptsidis, Advances in Radiation Oncology, Advances in Radiation Oncology, 2024 DOI:https://doi.org/10.1016/j.adro.2024.101570
• Exploring Automated Contouring Across Institutional Boundaries: A Deep Learning Approach with Mouse Micro-CT Datasets, Lu Jiang, Di Xu, Qifan Xu, Arion Chatziioannou, Keisuke S Iwamoto, Susanta Hui, Ke Sheng, arXiv:2405.18676 2024
• Paired Conditional Generative Adversarial Network for Highly Accelerated Liver 4D MRI, Di Xu, Xin Miao, Hengjie Liu, Jessica E. Scholey, Wensha Yang, Mary Feng, Michael Ohliger, Hui Lin, Yi Lao, Yang Yang, and Ke Sheng, Physics in Medicine and Biology, 2024 https://doi.org/10.1088/1361-6560/ad5489
• Feasibility Study of High-Power Electron Linac for Clinical X-ray ROAD-FLASH Therapy System, Sergey V. Kutsaev, Ronald Agustsson, Salime Boucher, Nasr Ghoniema, Kenichi Kaneta, Maksim Kravchenko, Adam Moro, Sohun Patela, Alan Li and Ke Sheng, Frontiers in Medical Engineering 2024  doi: 10.3389/fmede.2024.1382025, arXiv:2405.18676, 2024
• Intra-fractional geometric and dose/volume metric variations of magnetic resonance imaging-guided stereotactic radiotherapy of prostate bed after radical prostatectomy Yu Gao, Stephanie Yoon, Ting Martin Ma, Yingli Yang, Ke Sheng, Daniel A. Low, Leslie Ballas, Michael L. Steinberg, Amar U Kishan, Minsong Cao, Physics and Imaging in Radiation Oncology, 2024, DOI:https://doi.org/10.1016/j.phro.2024.100573
• Nodule detection and generation on chest X-rays: NODE21 Challenge, Ecem Sogancioglu, Bram van Ginneken, Finn Behrendt, Marcel Bengs, Alexander Schlaefer, Miron Radu, Di Xu, Ke Sheng, Fabien Scalzo, Eric Marcus, Samuele Papa, Jonas Teuwen, Ernst Th. Scholten, Steven Schalekamp, Nils Hendrix, Colin Jacobs, Ward Hendrix, Clara I S ́anchez, Keelin Murphy IEEE Transaction on Medical Imaging 2024 https://ieeexplore.ieee.org/document/10479589
• Deep Match: A Zero-Shot Data-Robust Framework for Improved Fiducial-free Lung Tumor Motion Tracking, Di Xu, Martina Descovich, Hengjie Liu, Yi Lao, Alexander R. Gottschalk, Ke Sheng, Radiotherapy and Oncology 2024 https://www.thegreenjournal.com/article/S0167-8140(24)00100-2/abstract
• Hypoxia-informed RBE-weighted beam orientation optimization for intensity-modulated proton therapy, Pavitra Ramesh, Dan Ruan, S. John Liu, Youngho Seo, Steve Braunstein, and Ke Sheng, Medical Physics 2024, https://doi.org/10.1002/mp.16978
• Learning Dynamic MRI Reconstruction with Convolutional Network Assisted Reconstruction Swin Transformer.  Xu, D., Liu, H., Ruan, D., Sheng, K. (2023). In: Woo, J., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2023 Workshops. MICCAI 2023. Lecture Notes in Computer Science, vol 14394. Springer, Cham. https://doi.org/10.1007/978-3-031-47425-5_1
• Robust Treatment Planning for Small Animal Radio-Neuromodulation Using Focused kV X-ray Beams, Chenhui Qiu, Wenbo Gu, Huagang Yan, Weiyuan Sun, Yuanyuan Wang, Qiang Wen, Ke Sheng, Wu Liu, Medical Physics 2024 DOI: 10.1002/mp.17023
• Dosimetric Predictors for Acute Genitourinary Toxicity in MR-guided Stereotactic Body Radiation Therapy (SBRT): Expanded Substructure with Fraction-wise Analysis, Jonathan Pham, Beth K. Neilsen, Hengjie Liu, Minsong Cao, Yingli Yang, Ke Shen, Ting Martin Ma, Amar U. Kishan, Dan Ruan, Medical Physics 2024 https://doi.org/10.1002/mp.16878

2023

• A Two-Step Framework for Multi-Material Decomposition of Dual Energy Computed Tomography from Projection Domain Di Xu, Qihui Lyu, Dan Ruan, Ke Sheng, arXiv:2311.00188
• Dosimetric Impact of Interfractional Bladder and Trigone Deformations: A Post-Hoc Analysis of a Phase III Randomized Trial of MRI-Guided vs. CT-Guided Stereotactic Body Radiotherapy in Prostate Cancer Beth K. Neilsen, Ting Martin Ma, Wisdom O. Akingbemi, John P. Neylon, Maria Casado, Sahil Sharma, Ke Sheng, Dan Ruan, Daniel Low, Yingli Yang, Luca F. Valle, Michael L Steinberg, James M. Lamb, Minsong Cao, Amar U. Kishan, International Journal of Radiation Oncology Biology and Physics 2023 https://www.redjournal.org/article/S0360-3016(23)08021-5/fulltext
• A Unified Path Seeking Algorithm for IMRT and IMPT Beam Orientation Optimization, Pavitra Ramesh, Gilmer Valdes, Daniel O'Connor, Ke Sheng, Physics in Medicine and Biology 2023 https://doi.org/10.1088/1361-6560/acf63f.
• Minimum Reporting Standards Should be Expected for Preclinical Radiobiology Irradiators and Dosimetry in the Published Literature, Poirier Y, DeWerd LA, Trompier F, Santos MD, Sheng K, Kunugi K, Satyamitra MM, DiCarlo AL, Winters TA,  Radiat Res. 2023 Aug 8. doi: 10.1667/RADE-23-00119.1.
  • Also appear in International Journal of Radiation Biology 2023 https://doi.org/10.1080/09553002.2023.2250848
• Contrast-enhanced Liver MR Synthesis using Gradient Regularized Multi-Modal Multi-Discrimination Sparse Attention Fusion GAN Changzhe Jiao, Diane Ling, Shelly Bian, April Vassantachart, Karen Cheng, Shahil Mehta, Derrick Lock, Zhenyu Zhu, Mary Feng, Horatio Thomas, Jessica E Scholey, Ke Sheng, Zhaoyang Fan, Wensha Yang, Cancers, 2023 Jul 8;15(14):3544. doi: 10.3390/cancers15143544.
• Gell: A GPU-powered 3D hybrid simulator for large-scale multicellular system, Jiayi Du, Yu Zhou, Lihua Jin, Ke Sheng, Plos ONE, 2023 Jul 18;18(7):e0288721. doi: 10.1371/journal.pone.0288721
• An Efficient and Robust Method for Chest X-ray Rib Suppression That Improves Pulmonary Abnormality Diagnosis Di Xu, Qifan Xu, Kevin Nhieu, Dan Ruan, Ke Sheng, Diagnostics (Basel) 2023 May 8;13(9):1652. doi: 10.3390/diagnostics13091652.
• Technical Note: Multi-MATE, A High-Throughput Platform For Automated Image-Guided Small-Animal Irradiation Jiang Lu, Pavitra Ramesh, Ryan Neph, Ke Sheng, Medical Physics 2023 https://doi.org/10.1002/mp.16563
• Analytical HDR Prostate Brachytherapy Planning with Automatic Catheter and Isotope Selection, C Holly Frank, Pavitra Ramesh, Qihui Lyu, Dan Ruan, Sangjune Park, Albert Chang, Puja Venkat, Amar U Kishan, Ke Sheng, Medical Physics 2023 http://doi.org/10.1002/mp.16677 
• Transformative Technology for FLASH Radiation Therapy Reinhard Schulte, Carol Johnstone, Salime Boucher, Eric Esarey, Cameron G. R. Geddes, Maksim Kravchenko, Sergey Kutsaev, Billy W. Loo, François Méot, Brahim Mustapha, Kei Nakamura, Emilio A. Nanni, Lieselotte Obst-Huebl, Stephen E. Sampayan, Carl B. Schroeder, Ke Sheng, Antoine M. Snijders, Emma Snively, Sami G. Tantawi and Jeroen Van Tilborg Appl. Sci. 2023, 13(8), 5021; https://doi.org/10.3390/app13085021
• Tomographic detection of photon pairs produced from high-energy X-rays for the monitoring of radiotherapy dosing, Qihui Lyu, Ryan Neph, Ke Sheng*, Nat Biomed Eng. 2023 Mar;7(3):323-334. doi: 10.1038/s41551-022-00953-8.2022 https://www.nature.com/articles/s41551-022-00953-8
• Magnetic resonance imaging-guided versus computed tomography-guided stereotactic body radiotherapy for prostate cancer (MIRAGE): Primary Endpoint Analysis of a Phase III Randomized Trial Amar U. Kishan Ting Martin Ma, James M. Lamb, Maria Casado, Holly Wilhalme, Daniel A. Low, Ke Sheng, Sahil Sharma, Yingli Yang, Yu Gao, John Neylon, Vincent Basehart, Minsong Cao, Michael L. Steinberg JAMA Oncol. 2023 Jan 12. doi: 10.1001/jamaoncol.2022.6558
• Mask R-CNN Assisted 2.5D Object Detection Pipeline of 68Ga-PSMA-11 PET/CT-positive Metastatic Pelvic Lymph Node After Radical Prostatectomy from solely CT Imaging, Di Xu, Martin Ma, Minsong Cao, Amar U. Kishan, Nicholas G. Nickols, Fabien Scalzo and Ke Sheng, Nat. Scientific Reports https://rdcu.be/c4sMd DOI:10.1038/s41598-023-28669-y

2022

• Gell: A GPU-powered 3D hybrid simulator for large-scale multicellular system Jiayi Du, Yu Zhou, Lihua Jin, Ke Sheng,  https://www.biorxiv.org/content/10.1101/2022.09.01.506296v1 doi.org/10.1101/2022.09.01.506296
• Dose and dose rate objectives in Bragg peak and shoot-through beam orientation optimization for FLASH proton therapy, Pavitra Ramesh, Wenbo Gu, Dan Ruan, Ke Sheng, Medical Physics, Med Phys. 2022 Oct 12. doi: 10.1002/mp.1600
• An efficient rectangular optimization method for sparse orthogonal collimator based small animal irradiation Lu Jiang, Qihui Lyu, Amr M H Abdelhamid, Susanta Hui, Ke Sheng, Physics and Medicine in Biology,  2022, doi:10.1088/1361-6560/ac910b
• Evaluation of T2-Weighted MRI for Visualization and Sparing of Urethra with MR-Guided Radiation Therapy (MRgRT) On-Board MRI. Pham J, Savjani RR, Gao Y, Cao M, Hu P, Sheng K, Low DA, Steinberg M, Kishan AU, Yang Y. Cancers (Basel). 2021 Jul 16;13(14):3564. doi: 10.3390/cancers13143564.
• Fully Automated Segmentation of Prostatic Urethra for MR-Guided Radiation Therapy (MRgRT), Di Xu, Ting Martin Ma, Ricky Savjani, Jonathan Pham, Minsong Cao, Yingli Yang, Amar U. Kishan, Fabien Scalzo, Ke Sheng* Medical Physics 2022 http://doi.org/10.1002/mp.15983
• Feasibility of a Novel Sparse Orthogonal Collimator–Based Preclinical Total Marrow Irradiation for Enhanced Dosimetric Conformality Amr M. H. Abdelhamid, Lu Jiang, Darren Zuro, An Liu, Srideshikan Sargur Madabushi, Hemendra Ghimire, Jeffrey Y. C. Wong, Simonetta Saldi, Christian Fulcheri, Claudio Zucchetti, Antonio Pierini, Ke Sheng, Cynthia Aristei and Susanta K. Hui Front. Oncol., 18 July 2022, https://doi.org/10.3389/fonc.2022.941814
• Reformulated McNamara RBE-weighted Beam Orientation Optimization for Intensity Modulated Proton Therapy, Pavitra Ramesh, Qihui Lyu, Wenbo Gu, Dan Ruan, and Ke Sheng, Med Phys. 2022 Apr;49(4):2136-2149. doi: 10.1002/mp.15552
• A Prospective Phase II Study of Automated Non-Coplanar VMAT for Recurrent Head and Neck Cancer:  Initial Report of Feasibility, Safety, and Patient Reported Outcomes Kaley Woods Ting Martin Ma, Kelsey Narahara, Zhouhuizi Shen, Eric Morris, Yu Gao, Kiri A. Cook, Ke Sheng, Amar U. Kishan, John V. Hegde, Carol Felix,  Vincent Basehart, Stephen Tenn, Michael Steinberg, Robert K. Chin MD, Minsong Cao Cancers 2022, 14(4), 939; https://doi.org/10.3390/cancers14040939
• Dosimetric Impact of Interfraction Prostate and Seminal Vesicle Volume Changes and Rotation: A Post-Hoc Analysis of a Phase III Randomized Trial of MRI-Guided versus CT-Guided Stereotactic Body Radiotherapy Ting Martin Ma, Minsong Cao, Jack Neylon, Maria Casado, Sahil Sharma, Ke Sheng, Daniel Low, Yingli Yang, Michael L. Steinberg, James Lamb, Amar U. Kishan, Radiotherapy and Oncology, Volume 167, February 2022, Pages 203-210  https://doi.org/10.1016/j.radonc.2021.12.037 
• To what extent can Plug-and-Play methods outperform neural networks alone in low-dose CT reconstruction, Qifan Xu, Qihui Lyu, Dan Ruan, Ke Sheng, ISBI 2022 https://arxiv.org/abs/2202.07173

2021

• Transformative Technology for FLASH Radiation Therapy: A Snowmass 2021 White Paper, S.Boucher, E. Esarey, C.G.R. Geddes, C. Johnstone, S. Kutsaev, B.W. Loo Jr., F. Méot, B. Mustapha, K. Nakamura, E. Nanni, L. Obst-Huebl, S.E. Sampayan, C. Schroeder, R. Schulte, K.Sheng, A. Snijders, E. Snively, S.G. Tantawi, J. van Tilborg, arXiv:2203.11047 https://doi.org/10.48550/arXiv.2203.11047
• Voxel-wise prediction of recurrent brain GBM via proximity estimation coupled multi-dimensional SVM Yi Lao, Dan Ruan, April Vassantachart, Zhaoyang Fan, Jason C. Ye, Eric L. Chang, Robert Chin, Tania Kaprealian, Gabriel Zada, Mark S Shiroishi,  Ke Sheng, and Wensha Yang, International Journal of Radiation.Oncology.Biology.Physics, 2021 https://doi.org/10.1016/j.ijrobp.2021.12.153
• Bladder surface dose modeling in prostate cancer radiotherapy: an analysis of motion-induced variations and the cumulative dose across the treatment. Yi Lao, Minsong Cao, Yingli Yang, Amar U. Kishan1, Wensha Yang, Yalin Wang, and Ke Sheng, Med Phys.2021;48:8024–8036, DOI: 10.1002/mp.15326
• Novel technologies for Linac-based radiotherapy Sergey V. Kutsaev, Salime Boucher, Brahim Mustapha, Ke Sheng Proceedings Volume 11838, Hard X-Ray, Gamma-Ray, and Neutron Detector Physics XXIII; 118380U (2021) https://doi.org/10.1117/12.2595707
• Clinical assessment of geometric distortion for a 0.35T MR-guided radiotherapy system. Neylon J, Cook KA, Yang Y, Du D, Sheng K, Chin RK, Kishan AU, Lamb JM, Low DA, Cao M. J Appl Clin Med Phys. 2021 Jul 7. doi: 10.1002/acm2.13340. Online ahead of print. PMID: 34231963
• Fixed Beamline Optimization for Intensity Modulated Carbon-Ion Therapy, Pavitra Ramesh, Hengjie Liu, Wenbo Gu, and Ke Sheng IEEE Transactions on Radiation and Plasma Medical Sciences 2021 DOI:10.1109/TRPMS.2021.3092296
• Using Neural Networks to Extend Cropped Medical Images for Deformable Registration Among Images with Differing Scan Extents, Elizabeth M. McKenzie, Nuo Tong, Dan Ruan, Minsong Cao, Robert K. Chin, Ke Sheng, Medical Physics 2021 48(8) 4459-4471 DOI: 10.1002/mp.15039 Editor's Choice
• Magnetic Resonance Imaging-Guided Stereotactic Body Radiotherapy for Prostate Cancer (MIRAGE): A Phase III Randomized Trial, Ting Martin Ma, James M. Lamb, Maria Casado, Xiaoyan Wang, T. Vincent Basehart, Yingli Yang, Daniel Low, Ke Sheng, Nzhde Agazaryan, Nicholas G. Nickols, Minsong Cao, Michael L. Steinberg, Amar U. Kishan BMC Cancer 2021 DOI: 10.1186/s12885-021-08281-x
• Automated Non-Coplanar VMAT for Dose Escalation in Recurrent Head and Neck Cancer Patients,  Kaley Woods, Robert K. Chin, Kiri A. Cook, Ke Sheng, Amar U. Kishan, John V. Hegde, Stephen Tenn, Michael Steinberg, Minsong Cao, Cancers, 2021 DOI: 10.3390/cancers13081910
• Yi Lao, Victoria Yu, Anthony Pham, Theodore Wang, Jing Cui, Audrey Gallogly, Eric Chang, Zhaoyang Fan, Tania Kaprealian, Wensha Yang, Ke Sheng*, Quantitative characterization of tumor proximity to stem cell niches: implications on recurrence and survival in GBM patients, Int. J. Radiation Oncology.Biology.Physics 2021 In press DOI: https://doi.org/10.1016/j.ijrobp.2021.02.020
• Victoria Y. Yu, Dan Nguyen, Daniel O’Connor, Dan Ruan, Tania Kaprealian, Robert Chin, Ke Sheng*, Treating Glioblastoma Multiforme (GBM) with super hyperfractionated radiation therapy: Implication of temporal dose fractionation optimization including cancer stem cell dynamics,  PLOS ONE 2021 https://doi.org/10.1371/journal.pone.0245676
• Weak Magnetic Fields Enhance the Efficacy of Radiotherapy Advances in Radiation Oncology, Robert Sandstrom, Mark Bryan, Yue Liu, Robin S Elgart, Ke Sheng, Michael Steinberg, William McBride, Daniel Low, Kei Iwamoto, Adv Radiat Oncol. 2021 Jan 16;6(3):100645. doi: 10.1016/j.adro.2021.100645.

2020

• DeepMC: A Deep Learning Method for Efficient Monte Carlo Beamlet Dose Calculation by Predictive Denoising in Magnetic Resonance-Guided Radiotherapy Ryan Neph, Qihui Lyu, Yangsibo Huang, You Ming Yang, Ke Sheng*, Physics and Medicine in Biology, 2020, DOI: 10.1088/1361-6560/abca01
• ROAD: ROtational direct Aperture optimization with a Decoupled ring-collimator for FLASH radiotherapy, Lyu, Qihui; Neph, Ryan; O'Connor, Daniel; Ruan, Dan; Boucher, Salime; Sheng, Ke*, Physics and Medicine in Biology, 2020, https://iopscience.iop.org/article/10.1088/1361-6560/abcbd0/meta
• Multi-task Edge-recalibrated Network for Male Pelvic Multi-Organ Segmentation on CT Images, Tong, Nuo; Gou, Shuiping; Chen, Shuzhe; Yao, Yao; Yang, Shuyuan; Cao, Minsong; Kishan, Amar; Sheng, Ke*, Physics and Medicine in Biology, 2020, DOI: 10.1088/1361-6560/abcad9
• Automatic detection and segmentation of multiple brain metastases on magnetic resonance image using asymmetric UNet architecture,  Cao, Yufeng; Vassantachart, April; Ye, Jason; Yu, Cheng; Ruan, Dan; Sheng, Ke; Lao, Yi; Shen, Zhilei; Balik, Salim; Bian, Shelly; Zada, Gabriel; Shiu, Almon; Chang, Eric; Yang, Wensha Physics and Medicine in Biology, 2020, DOI: 10.1088/1361-6560/abca53
• Analysis of Geometric Performance and Dosimetric Impact of using Automatic Contour Segmentation for Radiotherapy Planning, Minsong Cao, Bradley Stiehl, Victoria Yu, Ke Sheng, Amar Kishan, Robert K. Chin, Yingli Yang, Dan Ruan, Frontiers in Oncology 2020 https://doi.org/10.3389/fonc.2020.01762
• Practical Safety Considerations for Integration of Magnetic Resonance Imaging in Radiation Therapy, Minsong Cao, Brad Stiehl, Victoria Yu, Ke Sheng, Amar Kishan, Robert Chin, Yingli Yang, Dan Ruan, Practical Radiation Oncology, 2020 https://doi.org/10.1016/j.prro.2020.07.008
• Fraction-Variant Beam Orientation Optimization for Intensity-Modulated Proton Therapy, Wenbo Gu, Daniel O’Connor, Dan Ruan, Wei Zou, Lei Dong, and Ke Sheng, Medical Physics 2020 https://doi.org/10.1002/mp.14340
• Self-paced DenseNet with Boundary Constraint for Automated Multi-Organ Segmentation on Abdominal CT Images, Tong, Nuo; Gou, Shuiping; Niu, Tianye; Yang, Shuyuan; Sheng, Ke, Physics and Medicine in Biology 2020 65 135011 https://doi.org/10.1088/1361-6560/ab9b57
• Linear Energy Transfer Weighted Beam Orientation Optimization for Intensity-Modulated Proton Therapy, Wenbo Gu, Dan Ruan, Wei Zou, Lei Dong, and Ke Sheng, Medical Physics 2020 https://doi.org/10.1002/mp.14329
• Iterative reconstruction of cone-beam breast CT using plug-and-play projected gradient descent Qihui Lyu; Tianye Niu; Dan Ruan; Ke Sheng  Proc. SPIE 11312, Medical Imaging 2020: Physics of Medical Imaging, 113124J (16 March 2020); doi: 10.1117/12.2549787
• Deformable alignment of longitudinal postoperative brain GBM scans using deep learning Yi Lao; Victoria Yu; Eric Chang; Wensha Yang; Ke Sheng Proceedings Volume 11313, Medical Imaging 2020: Image Processing; 113130O (2020) https://doi.org/10.1117/12.2549129
• Quantifying vascular invasion in pancreatic cancer - a contrast CT based method for surgical resectability evaluation, Lao, Yi; David, John ; Fan, Zhaoyang; Bian, Shelly ; Shiu, Almon ; CHANG, ERIC; Sheng, Ke; Yang, Wensha; Tuli, Richard, Physics and Medicine in Biology, 2020 DOI: 10.1088/1361-6560/ab8106
• Artificial Intelligence in Radiotherapy: A Technological Review, Ke Sheng, Frontiers of Medicine, 2020 https://doi.org/10.1007/s11684-020-0761-1
• Self-Channel-and-Spatial-Attention Neural Network for Automated Multi-Organ Segmentation on Head and Neck CT Images, Tong, Nuo; Gou, Shuiping; Qi, Sharon; Yang, Shuyuan; Chin, Robert K.; Sheng, Ke, Physics and Medicine in Biology, 2020 accepted  https://iopscience.iop.org/article/10.1088/1361-6560/ab79c3
• A Novel Energy Layer Optimization Framework for Spot-Scanning Proton Arc Therapy, Wenbo Gu, Dan Ruan, Qihui Lyu, Wei Zou, Lei Dong, and Ke Sheng, Medical Physics, accepted 2020 https://aapm.onlinelibrary.wiley.com/doi/pdf/10.1002/mp.14083
• Many-isocenter Optimization for Robotic Radiotherapy, Qihui Lyu, Ryan Neph, Victoria Yu, Ran Ruan, Salime Boucher, Ke Sheng, Phys. Med. Biol. 65 (2020) 045003 (14pp) https://iopscience.iop.org/article/10.1088/1361-6560/ab63b8
• Image domain multi-material decomposition using single energy CT, Yi Xue, Yangkang Jiang, Pengfei Yang, Lei Xu, Chen Luo, Xi Hu, Jing Wang, Xiuhua Xu, Ke Sheng, Tianye Niu, Physics and Medicine in Biology, accepted 2020, https://iopscience.iop.org/article/10.1088/1361-6560/ab7503

2019

• Accurate Multi-Material Decomposition in Dual-Energy CT: A Phantom Study Yi Xue , Yangkang Jiang, Chunlin Yang, Qihui Lyu , Jing Wang, Chen Luo , Luhan Zhang, Catherine Desrosiers , Kun Feng, Xiaonan Sun, Xiuhua Hu, Ke Sheng, and Tianye Niu IEEE Transactions on Computational Imaging, vol. 5, no. 4, pp. 515-529, Dec. 2019, doi: 10.1109/TCI.2019.2909192.
• Multimodality Image Registration in the Head-and-Neck using a Deep Learning Derived Synthetic CT as a Bridge, Elizabeth McKenzie, Anand Santhanam, Dan Ruan, Daniel O'Connor, Minsong Cao, and Ke Sheng Medical Physics, 2019 47 (3) Pages 1094-1104, https://doi.org/10.1002/mp.13976
• Technical Note: Robust individual Thermoluminescence dosimeter tracking using optical fingerprinting Daili Shang, Wenbo Gu, Angelia Landers, Kaley Woods, Victoria Yu, Ryan Neph, Stephen Tenn, and Ke Sheng, Medical Physics 2019 https://doi.org/10.1002/mp.13895
• Fully Automated Pancreas Segmentation with Two-Stage 3D Convolutional Neural Networks, Ningning Zhao, Nuo Tong, Dan Ruan, and Ke ShengMICCAI 2019, LNCS 11765, pp. 201–209, 2019 https://doi.org/10.1007/978-3-030-32245-8_23
• DeepMCDose: A Deep Learning Method for Efficient Monte Carlo Beamlet Dose Calculation by Predictive Denoising in MR-Guided Radiotherapy  Ryan Neph, Yangsibo Huang, Youming Yang, and Ke Sheng, AIRT 2019, LNCS 11850, pp. 137–145, 2019. https://doi.org/10.1007/978-3-030-32486-5_17
• Image-domain multimaterial decomposition for dual-energy computed tomography with nonconvex sparsity regularization, Qihui Lyu, Daniel O’Connor, Tianye Niu, Ke Sheng*J. Med. Imag. 6(4), 044004 (2019), doi: 10.1117/1.JMI.6.4.044004
• Noise Suppression in Image-domain Multi-material Decomposition for Dual-energy CTs Yangkang Jiang, Yi Xue, Qihui Lyu, Lei Xu, Chen Luo, Pengfei Yang, Chunlin Yang, Jing Wang, Xi Hu, Xiaoqun Zhang, Ke Sheng, Tianye Niu IEEE Trans Biomed Eng 2019 DOI: 10.1109/TBME.2019.2916907
• A Sparse Orthogonal Collimator for Small Animal Intensity Modulated Radiation Therapy Part II: Hardware Development and Commissioning Kaley Woods, Ryan Neph, Dan Nguyen, Ke Sheng  Medical Physics 2019 DOI:10.1002/mp.13870
• A Sparse Orthogonal Collimator for Small Animal Intensity Modulated Radiation Therapy Part I: Planning System Development and Commissioning, Kaley Woods, Dan Nguyen, Ryan Neph, Dan Ruan, Daniel O’Connor, Ke Sheng, Medical Physics 2019 DOI:10.1002/mp.13872 Editor's Choice
• Automated 4π Radiotherapy Treatment Planning with Evolving Knowledge-Base Angelia Landers, Daniel O’Connor, Dan Ruan and Ke Sheng, Medical Physics 2019 https://doi.org/10.1002/mp.13651
• Parallel Beamlet Dose Calculation via Beamlet Contexts in a Distributed Multi-GPU Framework, R. Neph, C. Ouyang, J. Neylon, Y. M. Yang, and K. Sheng, Medical Physics 2019 June
• Robust Beam Orientation Optimization for Intensity-Modulated Proton Therapy  Wenbo Gu, Ryan Neph, Dan Ruan, Wei Zou, Lei Dong, and Ke Sheng, Medical Physics 2019 June  DOI:10.1002/mp.13641
• Scatter correction of cone-beam CT using a deep residual convolution neural network (DRCNN)  Jiang, Yangkang; Yang, Chunlin; Yang, Pengfei; Hu, Xi; Luo, Chen; Xue, Yi; Xu, Lei; Hu, Xiuhua; Zhang, Luhan; Wang, Jing; Sheng, Ke; Niu, Tianye, Physics in Medicine and Biology, 2019 64 145003
• Shape Constrained Fully Convolutional DenseNet with Adversarial Training for Multi-organ Segmentation on Head and Neck CT and Low Field MR Images Nuo Tong, Shuiping Gou, Shuyuan Yang, Minsong Cao, and Ke Sheng Medical Physics 2019 46 (6), June 2019 0094-2405 https://doi.org/10.1002/mp.13553
• Iterative reconstruction for low dose CT using Plug-and-Play alternating direction method of multipliers (ADMM) framework Qihui Lyu, Dan Ruan, John Hoffman, Ryan Neph, Michael McNitt-Gray, Ke Sheng Proceedings Volume 10949, Medical Imaging 2019: Image Processing; 1094906 (2019) https://doi.org/10.1117/12.2512484
• Image-domain multi-material decomposition for dual-energy CT with non-convex sparsity regularization Qihui Lyu, Daniel O'Connor, Tianye Niu, Ke Sheng, Proceedings Volume 10949, Medical Imaging 2019: Image Processing; 1094903 (2019) https://doi.org/10.1117/12.2508037
• Single-Arc VMAT optimization for Dual-Layer MLC, Qihui Lyu, Ryan Neph, Victoria Y Yu, Dan Ruan, Ke Sheng, Physics and Medicine in Biology, 2019 64 095028
• Motion Compensated Dynamic MRI Reconstruction with Local Affine Optical Flow Estimation , Ningning Zhao, Daniel O’Connor, Adrian Basarab, Dan Ruan, Ke Sheng, IEEE Transaction on Biomedical Engineering 2019 DOI:10.1109/TBME.2019.2900037

2018

• Robust Optimization for Intensity-Modulated Proton Therapy with Soft Spot Sensitivity Regularization, Wenbo Gu , Dan Ruan , Daniel O'Connor , Wei Zou , Lei Dong , Min-yu Tsai , Xun Jia , Ke Sheng, Medical Physics  2019 46 (3), 1408-1425 https://doi.org/10.1002/mp.13344
• Performance Comparison of Knowledge-Based Dose Prediction Techniques Based on Limited Patient Data, Angelia Landers, Ryan Neph, Fabien Scalzo, Dan Ruan, Ke Sheng, TCRT 2018
• Fully Automatic Multi-Organ Segmentation for Head and Neck Cancer Radiotherapy Using Shape Representation Model Constrained Fully Convolutional Neural Networks, Nuo Tong, Shuiping Gou, Shuyuan Yang, Dan Ruan and Ke Sheng Medical Physics 2018 45(10) 0094-2405 https://doi.org/10.1002/mp.13147
• A novel optimization framework for VMAT with dynamic gantry couch rotation, Lyu, Qihui; Yu, Victoria; Ruan, Dan; Neph, Ryan; O'Connor, Daniel; Sheng, Ke,  2018 Phys. Med. Biol. 63 125013
• Respiratory motion-resolved, self-gated 4D-MRI using rotating Cartesian k-space (ROCK): Initial clinical experience on an MRI-guided radiotherapy system Han F, Zhou Z, Du D, Gao Y, Rashid S, Cao M, Shaverdian N, Hegde JV, Steinberg M, Lee P, Raldow A, Low DA, Sheng K, Yang Y, Hu P.,Radiother Oncol. 2018 May 9. pii: S0167-8140(18)30221-4. doi: 10.1016/j.radonc.2018.04.029.
• A career path for pure academic medical physicists in radiation oncology should be established, Ke Sheng, Todd Pawlicki, Jing Cai, Medical Physics 2018  https://doi.org/10.1002/mp.12921
• Response to “in regard to “Tran A, Zhang J, Woods K, Yu V, Nguyen D, Gustafson G, Rosen L, Sheng K. Treatment planning comparison of IMPT, VMAT and 4π radiotherapy for prostate cases ”” Ke Sheng, Radiation Oncology 2018 13:66 https://doi.org/10.1186/s13014-018-1010-5
• VMAT optimization with dynamic collimator rotation , Qihui Lyu, Daniel O'Connor, Dan Ruan, Victoria Yu, Dan Nguyen, Ke Sheng, Medical Physics, 2018 https://doi.org/10.1002/mp.12915
• Technical note: Iterative Megavoltage CT (MVCT) Reconstruction using Block-Matching 3D-Transform (BM3D) Regularization , Qihui Lyu , Chunlin Yang , Hao Gao , Yi Xue , Daniel O'Connor , Tianye Niu , Ke Sheng*, Medical Physics 2018 https://doi.org/10.1002/mp.12916
• 4pi plan optimization for cortical-sparing brain radiotherapy Slava Murzin, Kaley Woods, Roshan Karunamuni, Tyler Seibert, Vitali Moiseenko, Daniel Simpson, Kathryn Tringale, Ke Sheng, Jona Hattangadi-Gluth, Radiotherapy and Oncology, Volume 127, Issue 1, April 2018, Pages 128-135  DOI: https://doi.org/10.1016/j.radonc.2018.02.011
• Cochlea-Sparing Acoustic Neuroma Treatment with 4pi Radiotherapy   Kaley Woods, Percy Lee, Tania Kaprealian, Isaac Yang, Ke Sheng, Advances in Radiation Oncology, 2018 In Press DOI: https://doi.org/10.1016/j.adro.2018.01.004
• Coupling reconstruction and motion estimation for dynamic MRI through optical flow constraint Ningning Zhao, Daniel O'Connor, Wenbo Gu, Dan Ruan, Adrian Basarab, and Ke Sheng Proceedings Volume 10574, Medical Imaging 2018: Image Processing; 1057429 (2018); doi: 10.1117/12.2293878
• Fraction-variant beam orientation optimization for non-coplanar IMRT  Daniel O'Connor, Victoria Yu, Dan Nguyen, Dan Ruan, Ke Sheng*,  Physics in Medicine and Biology, In Press 2018 doi: 10.1088/1361-6560/aaa94f.
• Integrated Beam Orientation and Scanning-Spot Optimization in Intensity Modulated Proton Therapy for Brain and Unilateral Head and Neck Tumors, Wenbo Gu, Daniel O'Connor, Dan Nguyen, Victoria Yu, Dan Ruan, Lei Dong, Ke Sheng*, Medical Physics,  45 (4) 2018 DOI: 10.1002/mp.12788 
• A Prospective 4pi Radiotherapy Clinical Study in Recurrent High Grade Glioma Patients,Victoria Yu, Angelia Tran, Kaley Woods, Minsong Cao, Robert Chin, Ke Sheng*, Tania Karealian*, Int. Journal of Radiation Oncology, Biology, Physics, Volume 101, Issue 1, 1 May 2018, Pages 144-151, https://doi.org/10.1016/j.ijrobp.2018.01.048

2017

• Radioresistance of the breast tumor is highly correlated to its level of cancer stem cell and its clinical implication for breast irradiation , X. Sharon Qi, Frank Pajonk, Susan McCloskey, Daniel A. Low, Patrick Kupelian, Michael Steinberg, Ke Sheng, Radiotherapy and Oncology, Volume 124, Issue 3, September 2017, Pages 455-461, https://doi.org/10.1016/j.radonc.2017.08.019
• Deterministic Direct Aperture Optimization Using Multiphase Piecewise Constant Segmentation, Dan Nguyen , Daniel O'Connor , Dan Ruan , Ke Sheng, Medical Physics 2017 44(10) DOI: 10.1002/mp.12529
• Multi-Institutional MicroCT Image Comparison of Image-Guided Small Animal Irradiators, Chris D. Johnstone, Patricia Lindsay, Edward E. Graves, Eugene Wong, Jessica R. Perez, Yannick Poirier, Youssef Ben-Bouchta, Thilakshan Kanesalingam, Haijian Chen, Ashley E. Rubinstein,  Ke Sheng, Magdalena Bazalova-Carter Phys. Med. Biol. 62 (2017) 5760–5776
• Predicting Liver SBRT Eligibility and Plan Quality for VMAT and 4π Plans, Angelia Tran; Kaley Woods; Dan Nguyen; Victoria Yu; Tianye Niu; Minsong Cao; Percy Lee; Ke Sheng* Radiation Oncology 201712:70 DOI: 10.1186/s13014-017-0806-z
• Treatment planning comparison of IMPT, VMAT and 4pi radiotherapy for prostate cases , Angelia Tran, Jingjing Zhang, Kaley Woods, Victoria Yu, Dan Nguyen, Gary Gustafson, Lane Rosen, and Ke Sheng* Radiation Oncology (2017) 12:10 DOI 10.1186/s13014-016-0761-0
• Feasibility evaluation of diffusion-weighted imaging using an integrated MRI-radiotherapy system for response assessment to neoadjuvant therapy in rectal cancer , Narek Shaverdian, Yingli Yang, Peng Hu, Steve Hart, Ke Sheng, James Lamb, Minsong Cao, Nzhde Agazaryan, David Thomas, Michael Steinberg, Daniel Low, Percy Lee. Br J Radiol. 2017 Mar;90(1071):20160739. doi: 10.1259/bjr.20160739. 
• Respiratory motion resolved, self-gated 4D-MRI using Rotating Cartesian K-space (ROCK) Fei Han, Ziwu Zhou, Minsong Cao, Yingli Yang, Ke Sheng, Peng Hu, Med Phys. 2017 Jan 30. doi: 10.1002/mp.12139. 

2016

• A Treatment Planning Comparison between Modulated Tri-Cobalt-60 Teletherapy and LINAC-Based Stereotactic Body Radiotherapy for Central Early-Stage Non-Small Cell Lung Cancer Catherine Merna, Jean-Claude M. Rwigema, Minsong Cao, Pin-Chieh Wang, Amar U. Kishan, Argin Michailian, James Lamb, Ke Sheng, Nzhde Agazaryan, Daniel A. Low, Patrick Kupelian, Michael L. Steinberg, Percy Lee 2016 Jan 2. pii: S0958-3947(15)00108-9. doi: 10.1016/j.meddos.2015.09.002.
• The Development and Verification of a Highly Accurate Collision Prediction Model for Automated Non-coplanar Plan Delivery , Victoria Y. Yu, Angelia Tran, Dan Nguyen, Minsong Cao, Dan Ruan, Daniel A. Low and Ke Sheng*, Medical Physics 42, 6457 (2015); doi: 10.1118/1.4932631
• Iterative CT shading correction with no prior information Pengwei Wu, Xiaonan Sun, Hongjie Hu, Tingyu Mao, Wei Zhao, Ke Sheng, Alice Cheung, Tianye Niu, Physics in Medicine and Biology 2015 Nov 7;60(21):8437-55. doi: 10.1088/0031-9155/60/21/84372015
• UTE-MRI-based Treatment Simulation and Patient Setup for Radiation Therapy of Brain Cancer , Yingli Yang, Minsong Cao, Tania Kaprealian, Ke Sheng Yu Gao, Fei Han, Caitlin Gomez, Anand Santhanam, Stephen Tenn, Daniel A Low, Peng Hu, Med. Phys. 43, 262 (2016); http://dx.doi.org/10.1118/1.4938266
• Viability of Non-Coplanar VMAT for Liver SBRT as Compared to Coplanar VMAT and Beam Orientation Optimized 4 IMRT Advances in Radiation Oncology Kaley Woods, Dan Nguyen, Angelia Tran, Victoria Y. Yu, Minsong Cao, Tianye Niu, Percy Lee, Ke Sheng*, Volume 1, Issue 1, January-March 2016, Pages 67-75 doi:10.1016/j.adro.2015.12.004
• A Novel Software and Conceptual Design of the Hardware Platform for Intensity Modulated Radiation Therapy , Dan Nguyen, Dan Ruan, Daniel O'Connor, Kaley Woods, Daniel A. Low, Salime Boucher, and Ke Sheng* Medical Physics 43, 917 (2016); doi: 10.1118/1.4940353
• Systematic feasibility analysis of a quantitative elasticity estimation for breast anatomy using supine/prone patient postures Katelyn Hasse*, John P Neylon , Ke Sheng, Anand Santhanam, Medical Physics 43, 1299 (2016); doi: 10.1118/1.4941745 82.
• Non-local means denoising of SG-KS-4D-MRI using block matching 3D: Implications for pancreatic tumor registration and segmentation , Jun Jin, Elizabeth Boehnke-McKenzie, Zhaoyan Fan, Richard Tuli, Ke Sheng, Howard Sandler Shuiping Gou, and Wensha Yang*, International Journal of Radiation Oncology, Biology, Physics Volume 95, Issue 3, 1 July 2016, Pages 1058-1066 http://dx.doi.org/10.1016/j.ijrobp.2016.02.006
• Non-local means denoising of SG-KS-4D-MRI using block matching 3D: Implications for pancreatic tumor registration and segmentation , Jun Jin, Elizabeth Boehnke-McKenzie, Zhaoyan Fan, Richard Tuli, Ke Sheng, Howard Sandler Shuiping Gou, and Wensha Yang*, International Journal of Radiation Oncology, Biology, Physics Volume 95, Issue 3, 1 July 2016, Pages 1058-1066 http://dx.doi.org/10.1016/j.ijrobp.2016.02.006
• Longitudinal Diffusion MRI for Treatment Response Assessment: Preliminary Experience using an MRI-Guided tri-Cobalt 60 Radiotherapy System , Yingli Yang, Minsong Cao, Ke Sheng, Yu Gao, Allen Chen, Mitchell Kamrava, Percy Lee, Nzhde Agazaryan, James Lamb, David Thomas, Daniel Low, Peng Hu, Medical Physics 43, 1369 (2016); doi: 10.1118/1.4942381
• Modeling and simulation of tumor-influenced high resolution real-time physics-based breast models for model-guided robotic interventions , John Neylon ; Katelyn Hasse ; Ke Sheng ; Anand P. Santhanam Proc. SPIE 9786, Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling, 97860X (March 18, 2016); doi:10.1117/12.2217028
• Feasibility of automated 3D MRI pancreas segmentation Shuiping Gou, Percy Lee, Peng Hu, Jean-Claude Rwigema, Ke Sheng* Advances in Radiation Oncology 2016 doi: 10.1016/j.adro.2016.05.002
• A Comprehensive Formulation for Volumetric Modulated Arc Therapy Planning Dan Nguyen, Qihui Lyu, Dan Ruan, Daniel O'Connor, Daniel A. Low, Ke Sheng* Medical Physics 43, 4263 (2016); doi: 10.1118/1.4953832
• Computerized triplet beam orientation optimization for MRI-guided Co-60 radiotherapy Dan Nguyen , David Thomas, Minsong Cao, Daniel O'Connor , James Lamb, Ke Sheng* Medical Physics 43, 5667 (2016); doi: 10.1118/1.4963212

2015

• A GPU based high-resolution multi-level biomechanical head and neck model for validating deformable image registration , John Neylon, Sharon Qi, Ke Sheng, Robert Staton, Jason Pukala, Rafael Manon, Daniel Low, Pat Kupelian, Anand Sathanam, Medical Physics 42, 232 (2015); doi: 10.1118/1.4903504
• Incorporating cancer stem cell in radiotherapy treatment response modeling and the implication in GBM treatment resistance Victoria Yu, Dan Nguyen, Frank Pajonk, Patrick Kupelian, Tania Kaprealian, Michael Selch, Daniel Low, and Ke Sheng* International Journal of Radiation Oncology, Biology, Physics Volume 91, Issue 4, 15 March 2015, Pages 866-875
• Noncoplanar beams improve dosimetry quality for extracranial intensity modulated radiotherapy and should be used more extensively Ke Sheng*, David M. Shepard and Colin G. Orton, Medical Physics 42, 531 (2015); doi: 10.1118/1.4895981
• 4pi Noncoplanar Stereotactic Body Radiation Therapy for Head and Neck Cancers - Potential to Improve Tumor Control and Late Toxicity. Rwigema JC; Nguyen D; Heron DE; Chen AM; Lee P; Wang P-C, Vargo JA; Low DA, Huq S; Tenn S, Steinberg ML, Kupelian P, Ke Sheng* .Int J Radiat Oncol Biol Phys. Volume 91, Issue 2, 1 February 2015, Pages 401-409
• Near Real-time Assessment of Anatomic and Dosimetric Variations for Head-and-Neck Radiotherapy via a GPU-based Dose Deformation Framework, X. Sharon Qi, Anand Santhanam, John Neylon, Yugang Min, Tess Armstrong, Ke Sheng, Robert J Staton, Jason Pukala, Andrew Pham, Daiel A. Low, Steve Lee, Michael Steinberg, Rafael Manon, Allen Chen, Patrick Kupelian. Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):415-22. doi: 10.1016/j.ijrobp.2015.01.033. Epub 2015 Apr 3.
• Dose Domain Optimization of MLC Leaf Patterns for Highly Complex IMRT Plans Dan Nguyen, Daniel O'Connor, Victoria Y. Yu, Dan Ruan, Minsong Cao, Daniel A. Low, Ke Sheng*, Medical Physics 42, 1858 (2015); doi: 10.1118/1.4915286
• Feasibility of MRI-guided Liver Stereotactic Body Radiotherapy: A Comparison Between Modulated Tri-Cobalt-60 Teletherapy and LINAC-Based Intensity Modulated Radiotherapy Amar U Kishan, Minsong Cao, Pin-Chieh Wang, Argin G Mikaeilian, Stephen Tenn, Jean-Claude M Rwigema, Ke Sheng, Daniel A Low, Patrick A Kupelian, Michael L Steinberg, Percy Lee. Practical Radaition Oncology 2015 Volume 5, Issue 5, Pages 330-337
• Lung dynamic MRI Deblurring Using Low-rank Decomposition and Dictionary Learning, Shuiping Gou, Yueyue Wang, Jiaolong Wu, Percy Lee, Ke Sheng*, Medical Physics 42, 1917 (2015); doi: 10.1118/1.4915543

2014

• Feasibility of robotic radiotherapy for prostate cancer, Peng Dong, Christopher King, Yingli Yang, Daniel Low, Edwin Romeijn, Troy Long, Patrick Kupelian, Michael Steinberg, Ke Sheng*, Practical Radiation Oncology, (2014) 4, 254-260 (cover article)
• Accelerating dynamic MRI for lung tumor tracking based on compressed sensing and low-rank decomposition in the spatial-temporal domain, a feasibility study Manoj Sarma, Peng Hu, Stan Rapacchi, Albert Thomas, Percy Lee, Patrick Kupelian, Ke Sheng* Int J Radiat Oncol Biol Phys 2014 Mar 1;88(3):723-31
• Integral Dose Investigation of Non-coplanar treatment beam geometries in Radiotherapy , Dan Nguyen, Peng Dong, Troy Long, Dan Ruan, Daniel A. Low, Edwin Romeijn, Ke Sheng*, Med. Phys. 41, 011905 (2014)
• Feasibility of Using Intermediate X-ray Energies for Highly Conformal Extracranial Radiotherapy Peng Dong, Victoria Yu, Dan Nguyen, John Demarco, Kaley Woods, Salime Boucher, Daniel A Low, Ke Sheng*, Med. Phys. 41, 041709 (2014)
• Pulmonary Toxicity in a Rabbit Model of Stereotactic Lung Radiation Therapy: Efficacy of a Radioprotector Jaime Mata, Ke Sheng, Klaus Hagspiel, Kai Ruppert, Peter Sylvester, John Mugler III, Carolina Fernandes, Steven Guan, James Larner, Paul Read, Experimental Lung Research 2014 Aug;40(6):308-16
• A non-voxel-based dose convolution/superposition algorithm optimized for scalable GPU architectures, John Neylon, Ke Sheng, Victoria Yu, Quan Chen, Patrick Kupelian, Daniel Low, Anand Santhanam, Med. Phys. 41, 101711 (2014); http://dx.doi.org/10.1118/1.4895822 .
• Correlation of Clinical and Dosimetric Parameters with Radiographic Lung Injury Following Stereotactic Body Radiotherapy, Amar U. Kishan, Pin-Chieh Wang, Victoria Yu, Dan Ruan, Minsong Cao, Steven Tenn, Ke Sheng, Daniel Low, Percy Lee Technology in Cancer Research and Treatment, 2014 DOI: 10.1177/1533034614551476
• Denoised and texture enhanced MVCT to improve soft tissue conspicuity, Ke Sheng*, Shuiping Gou, Jiaolong Wu, Sharon Qi, Medical Physics, 101916 (2014); doi: 10.1118/1.4894714
• Feasibility of automated pancreas segmentation based on dynamic MRI, Shuiping Gou, Jiaolong Wu, Fang Liu, Percy Lee, Stanislas Rapacchi, Peng Hu, Ke Sheng*, British Journal of Radiology, 2014 Dec;87(1044):20140248. doi: 10.1259/bjr.20140248
• Feasibility of extreme dose escalation for Glioblastoma Multiforme using 4pi radiotherapy, Dan Nguyen Jean-Claude Rwigema Victoria Yu Tania Kaprealian Patrick Kupelian Michael Selch Percy Lee Daniel Low and, Ke Sheng*, Radiat Oncol. 2014 Nov 7;9(1):239
• Evolution of Ipsilateral Head and Neck Radiotherapy. Ke Sheng*, Peng Dong, Archana Gautam, Chee-Wai Cheng, Dan Ruan, Daniel Low, Minsong Cao, Steve P. Lee and Patrick Kupelian Current Cancer Therapy Reviews, 2014, 10(4), 343 - 352

2013

• 4pi non-coplanar liver SBRT: a novel delivery technique, Peng Dong, Percy Lee, Daniel Low, Edwin Romeijn, Troy Long, Patrick Kupelian Ke Sheng* Int J Radiat Oncol Biol Phys. 2013. 85(5): p. 1360-1366.
• 4pi non-coplanar SBRT for centrally located or larger lung tumors, Peng Dong, Percy Lee, Yingli Yang, Daniel Low, Edwin Romeijn, Troy Long, Patrick Kupelian Ke Sheng*, Int J Radiat Oncol Biol Phys 2013 Jul 1;86(3):407-13
• Multidimensional MR Spectroscopic Imaging of Prostate Cancer In vivo, M.Albert Thomas, Rajakumar Nagarajan, Amir Huda, Daniel Margolis, Manoj K Sarma, Ke Sheng, Robert E Reiter, Steven S Raman, NMR in Biomedicine, 2013 Jul 31. doi: 10.1002/nbm.2991
• Multi-scale, multi-modal image integration for image-guided clinical interventions in the head and neck anatomy, Santhanam AP, Dou T, Neylon J, Min Y, Kupelian A, Ke Sheng, Ennis D, Rolland J, Low D, Kupelian P Stud Health Technol Inform. 2013;184:380-6.
• Valosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells, N Jiang, Y Shen, X Fei, Ke Sheng, P Sun, Y Qiu, J Larner, L Cao, X Kong*, and J Mi*, Cell Death and Disease (2013) 4, e647; doi:10.1038/cddis.2013.171
• Future of nanotechlogy in radiotherapy , Ke Sheng* Danial A. Low, ASTRO news letter Aug 2013

2012

• 3D Dose Verification Using Tomotherapy CT Detector Array Ke Sheng*, Wensha Yang, Ryan Jones, Paul Read Int J Radiat Oncol Biol Phys. Feb 1;82(2):1013-20. (2012) 
• TomoTherapy MLC verification using exit detector data Neal Dunlap,Quan Chen; Westerly, D.; Zhenyu Fang Ke Sheng, Yu Chen DMedical Physics 39(1): 143-52 (2012) . 
• MR spectroscopic imaging and diffusion-weighted imaging of prostate cancer with Gleason scores R. Nagarajan, D. Margolis, S. Raman, MK Sarma, Ke Sheng, C. King, G. Verma, J. Sayre, RE Reiter, MA Thomas J Magn Reson Imaging. 2012 May 11. doi: 10.1002/jmri.23676. 
• Computed Tomography-Based Anatomic Assessment Overestimates Local Tumor Recurrence in Patients With Mass-like Consolidation After Stereotactic Body Radiotherapy for Early-Stage Non-Small Cell Lung Cancer . Neal E Dunlap, Wensha Yang, Alyson McIntosh, Sheng K. Stanley H Benedict, Paul W Read, James M Larner International journal of radiation oncology, biology, physics. 08/2012; DOI:10.1016/j.ijrobp.2012.01.088

2011

• Standardized evaluation of simultaneous integrated boost plans on volumetric modulated arc therapy Wensha Yang, Ryan Jones, Stanley Benedict, Ke Sheng*, Phys. Med. Biol., 56(2):327-339 (2011) 
• Helical tomotherapy planning for lung cancer based on ventilation magnetic resonance imaging, Jing Cai, Stanley Benedict, Ke Sheng*, Med Dosim. Winter;36(4):389-96 (2011) 
• Use of MVCT with Image Registration for HDR Treatment Planning of an Oral Tongue Cancer Using a Custom Oral Mold Applicator with Embedded Lead Shielding, B. Libby, K. Sheng, R. McLawhorn, A. McIntosh, R. van Ausdal, A. Martof, P. Read Brachytherapy Jul-Aug;10(4):340-4 (2011). 
• Dosimetric comparison of 6 mv and 15 mv single arc rapidarc to helical tomotherapy for the treatment of pancreatic cancer   Jing Cai, Jinbo Yue, Robert McLawhorn, Wensha Yang, Krishni Wijesooriya, Neal E. Dunlap, Ke Sheng, Fang-fang Yin, Stanley H. BenedictMed Dosim. Autumn;36(3):317-20 (2011) 
• Correlation of Gleason scores with diffusion-weighted imaging findings of prostate cancer Nagarajan R, Margolis D, Raman S, Ke Sheng, King C, Reiter R, Thomas MA Adv Urol. 2012;2012:374805. Epub 2011 Dec 15 
• Quantification of regional lung ventilation from tagged hyperpolarized Helium-3 MRI. K. Ding, W. Miller, K. Cao, G. Christensen, J. Reinhardt, S. Benedict, B. Libby, K. Sheng*, IEEE-ISBI, Biomedical Imaging: From Nano to Macro, IEEE International Symposium pp1074 – 1077 (2011) 
• Feasibility of non-coplanar tomotherapy for lung cancer stereotactic body radiation therapy. Wensha Yang, Ryan Jones, Paul Read, James Larner, Ke Sheng*, Technol Cancer Res Treat. Aug;10(4):307-15 (2011) 
• Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastoma Shen Y, Wang Y, Sheng K, Fei X, Guo Q, Larner J, Kong X, Qiu Y, Mi J, Cell Death Dis. 2011 Dec 8;2:e241. doi: 10.1038/cddis.2011.126 
• Class Solution of Post-Mastectomy Radiation Therapy Using Tomotherapy Ryan Jones, Wensha Yang, Paul Read, Ke Sheng* Radiother Oncol. 2011 Aug;100(2):247-52 
• Helical tomotherapy simultaneous integrated boost provides a dosimetric advantage in the treatment of primary intracranial tumors Baisden, J. M. Sheehan, J. Reish, A. G., McIntosh, A. F., Sheng K. Read, P. W. Benedict, S. H., Larner, J. M, Neurol Res, 33(8) 820-4 (2011) 

2010

• Chest Wall Volume Receiving More than 30 Gy Predicts Risk of Severe Pain and/or Rib Fracture Following Lung Stereotactic Body Radiation Therapy Neal E. Dunlap, Jing Cai, Gregory B. Biedermann, Wensha Yang, Stanley H. Benedict, Ke Sheng, Tracey E. Schefter, Brian D. Kavanagh, James M. Larner, International Journal of Radiation Oncology • Biology. 2010 Mar 1;76(3):796-801.PMID: 19427740
• Intensity modulated radiation therapy (IMRT) outcomes for oropharyngeal squamous cell carcinoma patients stratified by p16 status . Asal Shoushtari MD Mathew Meeneghan, Ke Sheng, Christopher A Moskaluk, Christopher Y Thomas, James F Reibel, Paul A Levine, Mark J Jameson, Kimberly Keene, Paul W Read, Cancer. 2010 Jun 1;116(11):2645-54 PMID: 20225325
• Helical TomoTherapy-based STAT SBRT: Dosimetric Evaluation for a Real Time SBRT Treatment Planning and Delivery Program Neal Dunlap, Alyson McIntosh, Ke Sheng, Stanley Benedict, Benton Turner, Asal Shoushtari, Jason Sheehan, David R. Jones, James M. Larner,  Paul W. Read, Medical Dosimetry 2010 Winter;35(4):312-9(2010)
• Peripheral Non-small Cell Lung Cancers Treated With Stereotactic Body Radiation Therapy (SBRT). Dunlap NE, Larner JM, Read PW, Sheng K, David Jones. Size Matters: A Comparison of T1 and T2     The Journal of Thoracic and Cardiovascular Surgery.  2010 Sep;140(3):583-9.
• Effects of breathing variation on gating window internal target volume in respiratory gated radiation therapy. Cai J,  McLawhorn R, Read PW, Larner J, Benedict SH., Sheng K*. Med Phys. 2010 Aug;37(8):3927-34.
• Comparison of Elekta VMAT with helical tomotherapy and fixed field IMRT: Plan quality, delivery efficiency and accuracy Rao M, Yang WS, Chen F., Sheng K et al Med. Phys. (37)3 (2010) pp 1350-1359
• Helical TomoTherapy-based STAT SBRT: Dosimetric Evaluation for a Real Time SBRT Treatment Planning and Delivery Program Medical Dosimetry Neal Dunlap, Ke Sheng, Wensha Yang, Paul Read Med Dosim. 2010 Winter;35(4):312-9. 
• Apoptosis induced by the semiconductive nanoparticle/Photofrin conjugate in radiotherapy Li Wang, Wensha Yang, Paul Read, James Larner, Ke Sheng*, Nanotechnology. 2010 Nov 26;21(47):475103 (2010) 
• SRT and SBRT: Current practices for QA dosimetry and 3D S H Benedict, J Cai, B Libby, M Lovelock, D Schlesinger, K Sheng, and W Yang 2010 J. Phys.: Conf. Ser. 250 012057 doi:10.1088/1742-6596/250/1/012057 

2009

• A small animal irradiation platform for outcome assessment of lung stereotactic radiosurgery . Jing Cai, Talisa Altes, Jaime Mata, Ke Sheng* (Co-corresponding author), Paul Read, International Journal of Radiation Oncology • Biology (2009), 73(5), 1588-1595 PMID 19306756
• The implication of non-cyclic intrafractional longitudinal motion in SBRT by TomoTherapy. Wensha Yang, Ray Van Ausdal, Paul Read, James Larner, Stan Benedict, Ke Sheng* Physics in medicine and biology 54 (2009) 2875-2884 PMID 19384001
• Dynamic MRI of Grid-Tagged Hyperpolarized Helium-3 for the Assessment of Lung Motion during Breathing Jing Cai, Ke Sheng, Stanley H. Benedict, Paul W. Read, James M. Larner, John P. Mugler III, Eduard E. de Lange, Gordon D. Cates Jr. , G. Wilson Miller, International Journal of Radiation Oncology • Biology 2009 Sep 1;75(1):276-84. PMID: 19540059
• Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI , Xiaodong Zhong , David Schlesinger , Jason Sheehan , Craig Meyer , Frederick Epstein , James Larner , Paul Read , Stanley Benedict , Ke Sheng, Jing Cai. Medical Physics Journal 2009 Aug;36(8):3413-9  PMID: 19746774.
• Tumor Cell Survival Dependence on the Helical Tomotherapy, Continuous Arc and Segmented Dose Delivery Wensha Yang, Li Wang, James Larner,  Paul Read, Stan Benedict, Ke Sheng*. Physics in Medicine and Biology 2009 54(21):6635-43. PMID: 19826199

2008

2007

2006

2005

2000